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New England BioLabs, Ambion, and CRC Press


New England BioLabs has introduced its ShortCut RNAi kit, a system for the in vitro generation of short double-stranded RNA mixtures for RNAi experiments in mammalian cells.

The kit includes reagents for both high-yield in vitro transcription of large dsRNA and subsequent processing into short fragments, of 18 to 25 nucleotides, using highly concentrated RNase III with a modified reaction buffer containing manganese. The kit is good for 100 transfections and sells for $400.

Ambion recently launched its mirVana miRNA isolation kit, which is designed for the isolation of small RNAs — including micro RNA, short interfering RNA, and small nuclear RNA — from tissues and cells. Each kit can be used for up to 40 purifications, said Ambion, and sells for $200.

CRC Press has scheduled for publication a new book on RNA interference for mid-April next year. The book, called Gene Silencing by RNA Interference: Technology and Application, lists Muhammad Sohail from the University of Oxford as editor.

The text can be advance ordered at

The Scan

Not as High as Hoped

The Associated Press says initial results from a trial of CureVac's SARS-CoV-2 vaccine suggests low effectiveness in preventing COVID-19.

Finding Freshwater DNA

A new research project plans to use eDNA sampling to analyze freshwater rivers across the world, the Guardian reports.

Rise in Payments

Kaiser Health News investigates the rise of payments made by medical device companies to surgeons that could be in violation of anti-kickback laws.

Nature Papers Present Ginkgo Biloba Genome Assembly, Collection of Polygenic Indexes, More

In Nature this week: a nearly complete Ginkgo biloba genome assembly, polygenic indexes for dozens of phenotypes, and more.