New England BioLabs has introduced its ShortCut RNAi kit, a system for the in vitro generation of short double-stranded RNA mixtures for RNAi experiments in mammalian cells.

The kit includes reagents for both high-yield in vitro transcription of large dsRNA and subsequent processing into short fragments, of 18 to 25 nucleotides, using highly concentrated RNase III with a modified reaction buffer containing manganese. The kit is good for 100 transfections and sells for $400.

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Researchers suggest that genetic variations could influence the side effects people experience when using synthetic cannabinoids, the International Business Times reports.

An analysis has examined the makeup of researchers on Twitter and what they share, Nature News reports.

At Stat News, Jim Kozubek argues that the Broad Institute is pushing the boundary of what a nonprofit is.

In PNAS this week: gut microbes may affect honeybee weight, phenotype and gene expression changes in DiGeorge syndrome, and more.