NEW YORK (GenomeWeb) – A team led by researchers from the Massachusetts Institute of Technology this week published a study describing a new type of nanoparticle capable of delivering siRNAs to endothelial cells, while dodging hepatocytes and immune cells, at doses far lower than previously required.

The siRNA-loaded nanoparticles were also able to mediate highly durable non-liver gene silencing, further opening the door for RNAi as a therapeutic modality in diseases such as cancer and emphysema.

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In PLOS this week: Uncovering variants associated with diabetes-related kidney disease, a sequencing study of hepatitis E viruses circulating in Cambodia, and more.

Among Sacks' books was "Awakenings," which was later made into an Academy Award-winning film.

The popularity of the #sciencemoviequote Twitter trend showcases scientists' eclectic movie tastes and knack for puns. 

The popular astrophysicist warned that apathy and even contempt for science in politics could lead to the end of informed democracy. 

Sep
10
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In this online seminar, Jo Vandesompele of the Center for Medical Genetics at Ghent University will discuss methods for improving the analysis of microRNA expression from a range of samples.