By Doug Macron

Having taken the helm of Silence Therapeutics after the departure of its second chief executive in less than a year, the company's newly appointed CEO Tony Sedgwick sees continued advancement of the phase I cancer drug Atu027 as one of his key goals.

Meantime, Silence remains focused on demonstrating the potential of two new delivery technologies and expects to have a second clinical candidate incorporating one of them ready for human testing by early next year, Sedgwick said this week.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.