NEW YORK (GenomeWeb) – Researchers from the Massachusetts Institute of Technology this month reported new animal data showing that an endothelial cell-targeting nanoparticle can carry microRNAs and siRNAs into lung tumors and cause the cancer to regress.

The findings, which also show that the addition of chemotherapy to the small RNA treatment can further improve survival, point to the nanoparticle technology as yet another promising approach to overcoming the delivery challenge that has long hampered the development of nucleic acid medicines.

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