Mirna Publishes Data on Delivery of miRNA Mimics | GenomeWeb

Mirna Therapeutics said this week that it has published data in Molecular Therapy showing that a neutral lipid emulsion can be used to systemically deliver tumor-suppressing microRNA mimics and reduce tumor burden in mouse lungs.

In the paper, researchers from Mirna and Yale University used a transgenic mouse model of lung cancer to show that intravenous administration of the lipid-formulated mimics of miR-34 and let-7 triggered an RNAi response in cancer cells and inhibited tumor growth.

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