Skip to main content
Premium Trial:

Request an Annual Quote

MiReven Publishes Data on Role of microRNA in Cancer


Australian microRNA drug firm MiReven announced this week the publication of in vitro data validating the role of miR-7-5p in cancer.

The findings, which appeared in Biochemical and Biophysical Research Communications and were authored by a company co-founder, showed that the miRNA was reduced in metastatic melanoma-derived cell lines compared with primary melanoma cells.

Upon re-introduction of the miRNA and its ectopic expression, “migration and invasion of the melanoma cells was significantly inhibited in vitro,” the company said. The report also demonstrated that insulin receptor substrate-2 is a functional target of miR-7-5p, which then “decreases activity in the protein kinase B signaling pathway, a key regulator of many oncogenic processes including cell migration.”

MiReven is currently developing a miR-7 mimic as a treatment for cancer.

The Scan

More Boosters for US

Following US Food and Drug Administration authorization, the Centers for Disease Control and Prevention has endorsed booster doses of the Moderna and Johnson & Johnson SARS-CoV-2 vaccines, the Washington Post writes.

From a Pig

A genetically modified pig kidney was transplanted into a human without triggering an immune response, Reuters reports.

For Privacy's Sake

Wired reports that more US states are passing genetic privacy laws.

Science Paper on How Poaching Drove Evolution in African Elephants

In Science this week: poaching has led to the rapid evolution of tuskless African elephants.