By Doug Macron

This story has been updated to include company comment on its newly announced bladder cancer program.

MDRNA has begun non-human primate studies within its lead liver cancer program with the goal of selecting a lead drug candidate by the end of the year and potentially filing an investigational new drug application by late 2010, a company official said last week.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.