Marina Biotech this week reported a sharp rise in its fourth-quarter losses as the company recorded a restructuring charge related to a change made to a lease for a corporate facility.

For the three-month period ended Dec. 31, Marina's net loss rose to $5.9 million, or $0.23 per share, from a year-ago loss of $800,000, or $0.08 per share.

Revenues in the quarter rose to $1 million from $200,000, and include $800,000 in earn-out payments related to non-RNA-based legacy products from when the company was Nastech Pharmaceutical.