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Marina Posts Higher Q4 Losses on Restructuring Charge


Marina Biotech this week reported a sharp rise in its fourth-quarter losses as the company recorded a restructuring charge related to a change made to a lease for a corporate facility.

For the three-month period ended Dec. 31, Marina's net loss rose to $5.9 million, or $0.23 per share, from a year-ago loss of $800,000, or $0.08 per share.

Revenues in the quarter rose to $1 million from $200,000, and include $800,000 in earn-out payments related to non-RNA-based legacy products from when the company was Nastech Pharmaceutical.

Research and development spending for the fourth quarter edged up to $3.2 million from $3.1 million, while selling, general, and administrative costs fell to $1.6 million from $2.3 million year over year. The company also incurred a $3.5 million expense, primarily in the fourth quarter, related to an amended lease for a now-exited facility.

At the end of 2010, Marina had cash of approximately $2.1 million. Following a stock offering in February, which raised $5.1 million, Marina said it has enough resources to fund operations into the second quarter of this year.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.