Marina Gets Institutional Approval to Begin Phase I Study of FAP Drug | GenomeWeb

Marina Biotech said this week that it has received institutional site approval at Massachusetts General Hospital for its investigational familial adenomatous polyposis treatment CEQ508, clearing the way for initiation of a planned phase I study of the drug.

FAP is an inherited, colorectal cancer syndrome characterized by the growth of colorectal polyps. Though the polyps are initially benign, they become malignant in nearly all cases in the absence of colectomy, according to the company.

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