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Kreatech Biotechnology s Universal Linkage System, Ambion s Melt Total RNA Isolation System, and Promega s pGL4 Luciferase Reporter Vectors


Kreatech Biotechnology said this week that it has launched labeling kits for the DNA microarray market using the company’s Universal Linkage System labeling technology.

The ULS technology, said the company, relies on the special binding properties of transition metals to form coordinative bonds with biomolecules by binding to specific sites on DNA, RNA, and proteins.

Complete labeling kits include purification columns, blocking buffer, hybridization buffers, and ULS bound with the most common fluorescent dye pairs, including dyes from GE Healthcare, Invitrogen, PerkinElmer, and Dyomics.

Ambion has recently introduced the Melt Total RNA isolation system.

According to the company, the system is an alternative to traditional RNA isolation procedures that is also amenable to high-throughput tissue processing. Samples can be lysed quickly and easily in a closed-tube format that minimizes cross-contamination, said Ambion.

The system allows for the rapid digestion of fresh or frozen tissue, the company said. Following digestion, the RNA is purified using a streamlined process based on Ambion’s MagMax magnetic bead procedure.

Additional details about the system can be found at

Promega has introduced its pGL4 luciferase reporter vectors.

According to the company, the reporter gene vectors are optimized for expression in mammalian cells, and come in numerous configurations, including those with the synthetic luc2 (Photinus pyralis) and hRluc (Renilla reniformis) genes.

Both the reporter genes and the vector backbone have been engineered to reduce the number of consensus transcription factor binding sites, reducing background and the risk of anomalous transcription, Promega said.

Additional details about the vectors can be found at

The Scan

Not Yet a Permanent One

NPR says the lack of a permanent Food and Drug Administration commissioner has "flummoxed" public health officials.

Unfair Targeting

Technology Review writes that a new report says the US has been unfairly targeting Chinese and Chinese-American individuals in economic espionage cases.

Limited Rapid Testing

The New York Times wonders why rapid tests for COVID-19 are not widely available in the US.

Genome Research Papers on IPAFinder, Structural Variant Expression Effects, Single-Cell RNA-Seq Markers

In Genome Research this week: IPAFinder method to detect intronic polyadenylation, influence of structural variants on gene expression, and more.