Isis Team Reports on Identification of Argonaute-, RISC-Independent siRNAs | GenomeWeb

Researchers from Isis Pharmaceuticals this week reported in vitro evidence on the existence of a new class of siRNA, which can promote target RNA reduction independent of both Argonaute and RISC.

The authors of the study, which appeared in Nucleic Acids Research, caution that much work remains to be done before the significance of these siRNAs can be established, however.

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