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Isis, Lilly Antisense Drug Moves into Phase I Testing

Isis Pharmaceuticals said this week that the first antisense drug to come from the company’s collaboration with Eli Lilly has moved into phase I testing.

The drug, called LY2181308, targets survivin, a molecule that supports the survival of cells that would normally die through programmed cell death or apoptosis, said Isis. Survivin helps in the abnormal growth of cancer cells, and is found in many types of tumors, the company added.

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