HIV is a hot indication for potential RNAi-based therapeutics and CombiMatrix is getting ready to join the action. The Newport Beach, Calif.-based company said this week that its ongoing collaboration with Spanish non-profit research institute IrsiCaixa has yielded two promising siRNAs with anti-HIV activity, which are now being prepared for in vivo testing.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.