Title: Carbohydrate Conjugates as Delivery Agents for Oligonucleotides

Patent Number: 8,106,022

Filed: Dec. 4, 2008

Lead Inventor: Muthiah Manoharan, Alnylam Pharmaceuticals

The invention provides “iRNA agents” of a predefined formula, according to the patent's abstract.


Title: Method of Treating Cancer with an RPN2 Gene Expression Inhibitor

Patent Number: 8,106,024

Filed: June 15, 2004

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.