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IP Update: Recent Patents Awarded to UMass, Alnylam, DuPont, and more


Title: Compositions for RNA Interference and Methods of Use Thereof

Patent Number: 8,729,036

Filed: Aug. 7, 2003

Lead Inventor: Phillip Zamore, University of Massachusetts

Title: Method and Medicament for Inhibiting the Expression of a Given Gene

Patent Number: 8,729,037

Filed: Oct. 31, 2007

Lead Inventor: Roland Kreutzer, Alnylam Pharmaceuticals

Title: Downregulation of the Gene Expression by Means of Nucleic Acid-loaded Virus-like Particles

Patent Number: 8,729,038

Filed: Sept. 12, 2008

Lead Inventor: Jens Gruber, University of Amsterdam

Title: Compositions and Methods for Treating Hepatic Neoplasia

Patent Number: 8,729,041

Filed: Dec. 2, 2009

Lead Inventor: Joshua Mendell, Johns Hopkins University

Title: Supercoiled Minivectors for Gene Therapy Applications

Patent Number: 8,729,044

Filed: Oct. 15, 2010

Lead Inventor: Lynn Zechiedrich, Baylor College of Medicine

Title: Compositions and Methods for Short Interfering Nucleic Acid Inhibition of Nav1.8

Patent Number: 8,729,045

Filed: Oct. 16, 2012

Lead Inventor: Sameer Goregaoker, Merck

Title: Antisense Oligonucleotides for Inhibition of microRNA-21

Patent Number: 8,729,250

Filed: March 8, 2012

Lead Inventor: Joacim Elmen, Santaris Pharma

Title: Gene Silencing

Patent Number: 8,729,339

Filed: Dec. 18, 2007

Inventor: Milo Aukerman, DuPont

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.