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IP Update: Recent Patents Awarded to UMass, Alnylam, DuPont, and more


Title: Compositions for RNA Interference and Methods of Use Thereof

Patent Number: 8,729,036

Filed: Aug. 7, 2003

Lead Inventor: Phillip Zamore, University of Massachusetts

Title: Method and Medicament for Inhibiting the Expression of a Given Gene

Patent Number: 8,729,037

Filed: Oct. 31, 2007

Lead Inventor: Roland Kreutzer, Alnylam Pharmaceuticals

Title: Downregulation of the Gene Expression by Means of Nucleic Acid-loaded Virus-like Particles

Patent Number: 8,729,038

Filed: Sept. 12, 2008

Lead Inventor: Jens Gruber, University of Amsterdam

Title: Compositions and Methods for Treating Hepatic Neoplasia

Patent Number: 8,729,041

Filed: Dec. 2, 2009

Lead Inventor: Joshua Mendell, Johns Hopkins University

Title: Supercoiled Minivectors for Gene Therapy Applications

Patent Number: 8,729,044

Filed: Oct. 15, 2010

Lead Inventor: Lynn Zechiedrich, Baylor College of Medicine

Title: Compositions and Methods for Short Interfering Nucleic Acid Inhibition of Nav1.8

Patent Number: 8,729,045

Filed: Oct. 16, 2012

Lead Inventor: Sameer Goregaoker, Merck

Title: Antisense Oligonucleotides for Inhibition of microRNA-21

Patent Number: 8,729,250

Filed: March 8, 2012

Lead Inventor: Joacim Elmen, Santaris Pharma

Title: Gene Silencing

Patent Number: 8,729,339

Filed: Dec. 18, 2007

Inventor: Milo Aukerman, DuPont

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.