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IP Update: Recent Patents Awarded to Third Wave, Merck, Whitehead Institute

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Title: Detection of Small Nucleic Acids

Patent Number: 8,609,336

Filed: Feb. 7, 2012

Lead Inventor: James Dahlberg, Third Wave Technologies


Title: Methods and Compositions for RNA Interference

Patent Number: 8,609,830

Filed: May 17, 2004

Lead Inventor: Aimee Jackson, Merck


Title: Methods and Products for Expression of microRNAs

Patent Number: 8,609,832

Filed: Dec. 15, 2011

Lead Inventor: Chang-Zheng Chen, Whitehead Institute for Biomedical Research

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.