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IP Update: Recent Patents Awarded to Tekmira, Quark, and More

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Title: Lipid-containing Formulations

Patent Number: 8,642,076

Filed: Aug. 16, 2011

Lead Inventor: Muthiah Manoharan, Tekmira Pharmaceuticals (Alnylam Pharmaceuticals)


Title: Therapeutic Uses of Inhibitors of RTP801

Patent Number: 8,642,571

Filed: Aug. 31, 2012

Lead Inventor: Elena Feinstein, Quark Pharmaceuticals


Title: microRNA Inhibitors Comprising Locked Nucleotides

Patent Number: 8,642,751

Filed: Dec. 15, 2011

Lead Inventor: Christina Dalby, Miragen Therapeutics


Title: Detection of RNA in Tissue Samples

Patent Number: 8,644,580

Filed: Aug. 7, 2009

Inventor: David Lynch, Cambridge Research & Instrumentation

The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.