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IP Update: Recent Patents Awarded to Syngenta, UMass, and More

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Title: MADS Gene Regulatory Sequences for Expressing Gene Products in Plant Reproductive Tissue

Patent Number: 8,679,844

Filed: Oct. 28, 2011

Lead Inventor: Michael Nuccio, Syngenta


Title: RNA Interference for the Treatment of Gain-of-function Disorders

Patent Number: 8,680,063

Filed: Dec. 13, 2010

Lead Inventor: Neil Aronin, University of Massachusetts


Title: shRNA Gene Therapy for Treatment of Ischemic Heart Disease

Patent Number: 8,680,064

Filed: Sept. 15, 2009

Lead Inventor: Joseph Wu, Stanford University


Title: Methods for Producing Inducible and/or Repressible Expression Active Linear RNA Interference Cassettes and Inducible and/or Repressible Expression Active Linear Gene Cassettes and Their Use

Patent Number: 8,680,256

Filed: May 25, 2009

Inventor: Khalid Abu Khabar, King Faisal Specialist Hospital & Research Center


Title: Use of microRNAs to Control Virus Helper Nucleic Acids

Patent Number: 8,680,258

Filed: Nov. 25, 2009

Lead Inventor: Vernon Coffield, Alphavax


Title: Compositions of a Peptide Targeting System for Treating Cancer

Patent Number: 8,680,045

Filed: Nov. 1, 2011

Lead Inventor: Thomas Primiano, PeptiMed


Title: Targeting microRNAs for the Treatment of Cancer

Patent Number: 8,680,067

Filed: May 25, 2012

Lead Inventor: Frank Bennett, Regulus Therapeutics

The Scan

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.

Study Highlights Pitfall of Large Gene Panels in Clinical Genomic Analysis

An analysis in Genetics in Medicine finds that as gene panels get larger, there is an increased chance of uncovering benign candidate variants.

Single-Cell Atlas of Drosophila Embryogenesis

A new paper in Science presents a single-cell atlas of fruit fly embryonic development over time.

Phage Cocktail Holds Promise for IBD

Researchers uncovered a combination phage therapy that targets Klebsiella pneumonia strains among individuals experiencing inflammatory bowel disease flare ups, as they report in Cell.