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IP Update: Recent Patents Awarded to Syngenta, UMass, and More

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Title: MADS Gene Regulatory Sequences for Expressing Gene Products in Plant Reproductive Tissue

Patent Number: 8,679,844

Filed: Oct. 28, 2011

Lead Inventor: Michael Nuccio, Syngenta


Title: RNA Interference for the Treatment of Gain-of-function Disorders

Patent Number: 8,680,063

Filed: Dec. 13, 2010

Lead Inventor: Neil Aronin, University of Massachusetts


Title: shRNA Gene Therapy for Treatment of Ischemic Heart Disease

Patent Number: 8,680,064

Filed: Sept. 15, 2009

Lead Inventor: Joseph Wu, Stanford University


Title: Methods for Producing Inducible and/or Repressible Expression Active Linear RNA Interference Cassettes and Inducible and/or Repressible Expression Active Linear Gene Cassettes and Their Use

Patent Number: 8,680,256

Filed: May 25, 2009

Inventor: Khalid Abu Khabar, King Faisal Specialist Hospital & Research Center


Title: Use of microRNAs to Control Virus Helper Nucleic Acids

Patent Number: 8,680,258

Filed: Nov. 25, 2009

Lead Inventor: Vernon Coffield, Alphavax


Title: Compositions of a Peptide Targeting System for Treating Cancer

Patent Number: 8,680,045

Filed: Nov. 1, 2011

Lead Inventor: Thomas Primiano, PeptiMed


Title: Targeting microRNAs for the Treatment of Cancer

Patent Number: 8,680,067

Filed: May 25, 2012

Lead Inventor: Frank Bennett, Regulus Therapeutics

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.