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IP Update: Recent Patents Awarded to Syngenta, UMass, and More


Title: MADS Gene Regulatory Sequences for Expressing Gene Products in Plant Reproductive Tissue

Patent Number: 8,679,844

Filed: Oct. 28, 2011

Lead Inventor: Michael Nuccio, Syngenta

Title: RNA Interference for the Treatment of Gain-of-function Disorders

Patent Number: 8,680,063

Filed: Dec. 13, 2010

Lead Inventor: Neil Aronin, University of Massachusetts

Title: shRNA Gene Therapy for Treatment of Ischemic Heart Disease

Patent Number: 8,680,064

Filed: Sept. 15, 2009

Lead Inventor: Joseph Wu, Stanford University

Title: Methods for Producing Inducible and/or Repressible Expression Active Linear RNA Interference Cassettes and Inducible and/or Repressible Expression Active Linear Gene Cassettes and Their Use

Patent Number: 8,680,256

Filed: May 25, 2009

Inventor: Khalid Abu Khabar, King Faisal Specialist Hospital & Research Center

Title: Use of microRNAs to Control Virus Helper Nucleic Acids

Patent Number: 8,680,258

Filed: Nov. 25, 2009

Lead Inventor: Vernon Coffield, Alphavax

Title: Compositions of a Peptide Targeting System for Treating Cancer

Patent Number: 8,680,045

Filed: Nov. 1, 2011

Lead Inventor: Thomas Primiano, PeptiMed

Title: Targeting microRNAs for the Treatment of Cancer

Patent Number: 8,680,067

Filed: May 25, 2012

Lead Inventor: Frank Bennett, Regulus Therapeutics

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.