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IP Update: Recent Patents Awarded to Sylentis, Senesco, CalTech, and More


Title: Sphinogosine-bound siRNA

Patent Number: 8,703,731

Filed: June 22, 2010

Lead Inventor: Ana Jimenez, Sylentis

Title: Disulfide-linked Polyethylene Glycol/Peptide Conjugates for the Transfection of Nucleic Acids

Patent Number: 8,703,906

Filed: Sept. 3, 2010

Lead Inventor: Patrick Baumhof, CureVac

Title: Compositions and Method for Delivering Inhibitory Oligonucleotides

Patent Number: 8,703,921

Filed: April 15, 2009

Lead Inventor: Bira Arya, Department of Health and Human Services

Title: Compositions Comprising siRNA and Plasmids

Patent Number: 8,703,929

Filed: March 9, 2009

Lead Inventor: Richard Dondero, Senesco Technologies

Title: microRNA Inhibition for the Treatment of Inflammation and Myeloproliferative Disorders

Patent Number: 8,697,672

Filed: May 16, 2008

Lead Inventor: David Baltimore, California Institute of Technology

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.