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IP Update: Recent Patents Awarded to Sylentis, Senesco, CalTech, and More


Title: Sphinogosine-bound siRNA

Patent Number: 8,703,731

Filed: June 22, 2010

Lead Inventor: Ana Jimenez, Sylentis

Title: Disulfide-linked Polyethylene Glycol/Peptide Conjugates for the Transfection of Nucleic Acids

Patent Number: 8,703,906

Filed: Sept. 3, 2010

Lead Inventor: Patrick Baumhof, CureVac

Title: Compositions and Method for Delivering Inhibitory Oligonucleotides

Patent Number: 8,703,921

Filed: April 15, 2009

Lead Inventor: Bira Arya, Department of Health and Human Services

Title: Compositions Comprising siRNA and Plasmids

Patent Number: 8,703,929

Filed: March 9, 2009

Lead Inventor: Richard Dondero, Senesco Technologies

Title: microRNA Inhibition for the Treatment of Inflammation and Myeloproliferative Disorders

Patent Number: 8,697,672

Filed: May 16, 2008

Lead Inventor: David Baltimore, California Institute of Technology

The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.