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IP Update: Recent Patents Awarded to Silence Therapeutics, UMass, and More

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Title: Compositions and Methods for Treatment of Prostate and Other Cancer

Patent Number: 8,722,872

Filed: June 23, 2009

Lead Inventor: Martin Gleave, University of British Columbia


Title: Method of Modifying the Carbohydrate Content of a Plant

Patent Number: 8,729,338

Filed: Sept. 17, 2010

Lead Inventor: Gino Boussiengui-Boussiengui, Stellenbosch University


Title: Means for Inhibiting the Expression of Orc-1

Patent Number: 8,722,875

Filed: Sept. 23, 2009

Lead Inventor: Manfred Gossen, Silence Therapeutics


Title: AAVs and Uses Thereof

Patent Number: 8,734,809

Filed: April 23, 2010

Lead Inventor: Guangping Gao, University of Massachusetts


Title: HDL particles for Delivery of Nucleic Acids

Patent Number: 8,734,853

Filed: Nov. 17, 2009

Lead Inventor: Anil Sood, University of Texas


Title: shRNA Molecules and Methods of Use Thereof

Patent Number: 8,735,058

Filed: June 29, 2012

Inventor: Donald Rao, Gradalis


Title: Methods for Creating and Identifying Functional RNA Interference Elements

Patent Number: 8,735,064

Filed: Dec. 23, 2008

Lead Inventor: David Micklem, Bergenbio


Title: Compositions and Methods for Inhibiting Expression of a Gene from the Ebola Virus

Patent Number: 8,735,369

Filed: Sept. 26, 2012

Lead Inventor: Sina Bavari, Alnylam Pharmaceuticals


Title: Compositions and Methods for Altering RNAi

Patent Number: 8,735,371

Filed: Nov. 5, 2012

Lead Inventor: Richard Carthew, Northwestern University


Title: Lipids, Lipid Complexes, and Use Thereof

Patent Number: 8,735,453

Filed: Jan. 16, 2013

Lead Inventor: Oliver Keil, Silence Therapeutics


Title: Bacterially Derived Intact Minicells that Encompass Plasmid-free Functional Nucleic Acid for In Vivo Delivery to Mammalian Cells

Patent Number: 8,735,566

Filed: March 21, 2008

Lead Inventor: Himanshu Brahmbhatt, Engeneic Molecular Delivery


Title: Multi-targeted RNAi Therapeutics for Scarless Wound Healing of Skin

Patent Number: 8,735,567

Filed: Nov. 6, 2008

Lead Inventor: Patrick Lu, Sirnaomics


Title: Endogenous Regulator of RNA Silencing in Plants

Patent Number: 8,735,653

Filed: June 2, 2005

Lead Inventor: Vicki Vance, University of South Carolina

The Scan

Review of Approval Process

Stat News reports the Department for Health and Human Services' Office of the Inspector General is to investigate FDA's approval of Biogen's Alzheimer's disease drug.

Not Quite Right

A new analysis has found hundreds of studies with incorrect nucleotide sequences reported in their methods, according to Nature News.

CRISPR and mRNA Together

Time magazine reports on the use of mRNA to deliver CRISPR machinery.

Nature Papers Present Smartphone Platform for DNA Diagnosis of Malaria, Mouse Lines for Epigenomic Editing

In Nature this week: a low-cost tool to detect infectious diseases like malaria, and more.