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IP Update: Recent Patents Awarded to Quark, Regulus, Alnylam, and More


Title: Oligoribonucleotides and Methods of Use Thereof for Treatment of Alopecia, Acute Renal Failure, and Other Diseases

Patent Number: 8,765,699

Filed: Sept. 27, 2005

Lead Inventor: Elena Feinstein, Quark Pharmaceuticals

Title: Oligomeric Compounds and Compositions for Use in Modulation of Small Non-coding RNAs

Patent Number: 8,765,701

Filed: Dec. 30, 2008

Lead Inventor: Frank Bennett, Regulus Therapeutics

Title: Modified Small Interfering RNA Molecules and Methods of Use

Patent Number: 8,765,704

Filed: Dec. 14, 2011

Lead Inventor: Jang Han, Novartis

Title: Oligonucleotides Inhibiting Cellular Migration

Patent Number: 8,765,705

Filed: July 30, 2010

Lead Inventor: Florence Cabon, National Center for Scientific Research

Title: microRNA-104-5p as a Tumor Suppressor and Sensitizing Agent for Chemotherapy

Patent Number: 8,765,707

Filed: April 23, 2012

Lead Inventor: Preethi Gunaratne, Baylor College of Medicine

Title: Methods and Composition involving miRNA and miRNA Inhibitor Molecules

Patent Number: 8,765,709

Filed: Aug. 28, 2013

Lead Inventor: David Brown, Asuragen

Title: RNA Interference-mediating Small RNA Molecules

Patent Number: 8,765,930

Filed: June 4, 2010

Lead Inventor: Thomas Tuschl, Max Planck Institute (Massachusetts Institute of Technology, Whitehead Institute for Biomedical Research, University of Massachusetts)

Title: Double-stranded Oligonucleotide Compound for Down-regulating the Expression of CASP2 Gene

Patent Number: 8,765,931

Filed: Oct. 22, 2009

Lead Inventor: Elena Feinstein, Quark Pharmaceuticals

Title: Compositions and Methods for Inhibiting Expression of XBP-1 Gene

Patent Number: 8,765,932

Filed: Sept. 14, 2012

Lead Inventor: Kevin Fitzgerald, Alnylam Pharmaceuticals

Title: miRNA Target Prediction

Patent Number: 8,768,630

Filed: Feb. 22, 2011

Lead Inventor: Inhan Lee, University of Michigan

The Scan

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.

Algorithm Teases Out Genetic Ancestry in Individuals at Biobank Scale

Researchers develop an algorithm known as Rye to tease apart ancestry fractions in admixed individuals at a biobank-scale, applying it to 488,221 UK Biobank participants in Nucleic Acids Research.

Multi-Ancestry Analysis Highlights Comparable Common Variants at Complex Trait-Linked Loci

Researchers in Nature Genetics examine common variants implicated in more than three dozen conditions, estimating genetic effect similarities across ancestry tracts in admixed individuals.

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.