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IP Update: Recent Patents Awarded to OSU, Gradalis, Novartis, and More

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Title: Methods for Diagnosing Breast Cancer Using microRNAs

Patent Number: 8,603,744

Filed: Feb. 28, 2012

Lead Inventor: Carlo Croce, Ohio State University


Title: Individualized Cancer Therapy

Patent Number: 8,603,991

Filed: Nov. 17, 2006

Lead Inventor: David Shanahan, Gradalis


Title: dsRNA for Treating Viral Infection

Patent Number: 8,603,995

Filed: Jan. 26, 2012

Lead Inventor: Mark Labow, Novartis


Title: siRNA That Inhibits WT1 Gene Expression and Uses Thereof

Patent Number: 8,603,997

Filed: Oct. 24, 2012

Lead Inventor: Haruo Sugiyama, Osaka University

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.