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IP Update: Recent Patents Awarded to NYU, UMass, City of Hope, and More

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Title: Composition for Nucleic Acid Delivery Using Metal Nanoparticles and Preparing Method Thereof

Patent Number: 8,747,903

Filed: March 27, 2012

Lead Inventor: Sei Kwang Hahn, Postech Academy-Industry Foundation


Title: RNA-containing Modified Nucleosides and Methods of Use Thereof

Patent Number: 8,748,089

Filed: March 15, 2013

Lead Inventor: Katalin Kariko, University of Pennsylvania


Title: Compositions and Methods for Diagnosing and Treatment Melanoma

Patent Number: 8,748,098

Filed: Aug. 8, 2012

Lead Inventor: Eva Hernando, New York University


Title: Modulation of HSV Infection

Patent Number: 8,748,403

Filed: Jan. 21, 2005

Lead Inventor: Evelyn Kurt-Jones, University of Massachusetts


Title: Methods and Compositions for the Treatment of Cancer or Other Diseases

Patent Number: 8,748,405

Filed: Sept. 9, 2011

Lead Inventor: Hua Yu, City of Hope


Title: Preventative for Adhesion following Abdominal Surgery

Patent Number: 8,748,406

Filed: June 29, 2012

Lead Inventor: Takashi Muramatsu, Medical Therapies Limited


Title: siRNA for Inhibition of OTUB1 Expression and Pharmaceutical Composition Containing the Same

Patent Number: 8,748,592

Filed: Feb. 6, 2013

Lead Inventor: Eun Joo Song, Korea Institute of Technology


Title: Low Molecular Weight Cationic Lipids for Oligonucleotide Delivery

Patent Number: 8,748,667

Filed: May 31, 2011

Lead Inventor: Brian Budzik, Merck (Alnylam Pharmaceuticals)


Title: Carrier Nanoparticles and Related Compositions, Methods, and Systems

Patent Number: 8,746,999

Filed: March 28, 2013

Lead Inventor: Mark Davis, California Institute of Technology

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.