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IP Update: Recent Patents Awarded to NYU, UMass, City of Hope, and More

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Title: Composition for Nucleic Acid Delivery Using Metal Nanoparticles and Preparing Method Thereof

Patent Number: 8,747,903

Filed: March 27, 2012

Lead Inventor: Sei Kwang Hahn, Postech Academy-Industry Foundation


Title: RNA-containing Modified Nucleosides and Methods of Use Thereof

Patent Number: 8,748,089

Filed: March 15, 2013

Lead Inventor: Katalin Kariko, University of Pennsylvania


Title: Compositions and Methods for Diagnosing and Treatment Melanoma

Patent Number: 8,748,098

Filed: Aug. 8, 2012

Lead Inventor: Eva Hernando, New York University


Title: Modulation of HSV Infection

Patent Number: 8,748,403

Filed: Jan. 21, 2005

Lead Inventor: Evelyn Kurt-Jones, University of Massachusetts


Title: Methods and Compositions for the Treatment of Cancer or Other Diseases

Patent Number: 8,748,405

Filed: Sept. 9, 2011

Lead Inventor: Hua Yu, City of Hope


Title: Preventative for Adhesion following Abdominal Surgery

Patent Number: 8,748,406

Filed: June 29, 2012

Lead Inventor: Takashi Muramatsu, Medical Therapies Limited


Title: siRNA for Inhibition of OTUB1 Expression and Pharmaceutical Composition Containing the Same

Patent Number: 8,748,592

Filed: Feb. 6, 2013

Lead Inventor: Eun Joo Song, Korea Institute of Technology


Title: Low Molecular Weight Cationic Lipids for Oligonucleotide Delivery

Patent Number: 8,748,667

Filed: May 31, 2011

Lead Inventor: Brian Budzik, Merck (Alnylam Pharmaceuticals)


Title: Carrier Nanoparticles and Related Compositions, Methods, and Systems

Patent Number: 8,746,999

Filed: March 28, 2013

Lead Inventor: Mark Davis, California Institute of Technology

The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.