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IP Update: Recent Patents Awarded to Dicerna, Roche, RXi, and More


Title: Compositions and Methods for Immunostimulatory RNA Oligonucleotides

Patent Number: 8,815,503

Filed: Sept. 14, 2006

Lead Inventor: Gunther Hartmann, University of Bonn

Title: Use of Regulatory Sequences for Specific, Transient Expression in Neuronal Determined Cells

Patent Number: 8,815,505

Filed: Sept. 30, 2010

Lead Inventor: Sebastien Couillard-Despres, Roche

Title: Modulation of Gene Expression Using Oligomers that Target Gene Regions Downstream of 3' UTR Regions

Patent Number: 8,815,586

Filed: April 23, 2010

Lead Inventor: David Corey, University of Texas

Title: Phagocytic Cell Delivery of RNAi

Patent Number: 8,815,818

Filed: July 17, 2009

Lead Inventor: Dmitry Samarsky, RXi Pharmaceuticals

Title: Antiviral Therapy

Patent Number: 8,815,820

Filed: March 30, 2010

Inventor: Amy Buck, University of Edinburgh

Title: Double-stranded Oligonucleotides

Patent Number: 8,815,821

Filed: Oct. 20, 2011

Inventor: Tod Woolf, Life Technologies

Title: Methods and Compositions for the Specific Inhibition of Beta-catenin by Double-stranded RNA

Patent Number: 8,815,825

Filed: Dec. 18, 2012

Lead Inventor: Bob Brown, Dicerna Pharmaceuticals

Title: Anti-microRNA Oligonucleotide Molecules

Patent Number: 8,816,060

Filed: Nov. 13. 2012

Lead Inventor: Thomas Tuschl, Rockefeller University

Title: Method to Trigger RNA Interference

Patent Number: 8,816,061

Filed: March 14, 2013

Lead Inventor: James Carrington, Oregon State University

The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.