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IP Update: Recent Patents Awarded to Devgen, Alnylam, Alcon, and More

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Title: Methods and Compositions for Increasing RNA Interference

Patent Number: 8,865,668

Filed: Feb. 20, 2009

Lead Inventor: Romaan Raemaekers, Devgen (Syngenta)


Title: RNAi-mediated Inhibition of TNA-alpha Signaling Pathway for Treatment of Glaucoma

Patent Number: 8,865,670

Filed: Feb. 10, 2011

Lead Inventor: Jon Chatterton, Alcon


Title: RNAi-mediated Inhibition of Spleen Tyrosine Kinase-related Inflammatory Conditions

Patent Number: 8,865,671

Filed: June 30, 2011

Lead Inventor: John Yanni, Alcon


Title: Compositions and Methods for Silencing Apolipoprotein B

Patent Number: 8,865,675

Filed: May 12, 2011

Lead Inventor: James Heyes, Protiva Biotherapeutics (Tekmira Pharmaceuticals)


Title: Methods and Kits for Synthesis of siRNA Expression Cassettes

Patent Number: 8,865,676

Filed: Jan. 31, 2013

Lead Inventor: John Rossi, City of Hope


Title: iRNA Agents with Biocleavable Tethers

Patent Number: 8,865,677

Filed: March 22, 2013

Lead Inventor: Muthiah Manoharan, Alnylam Pharmaceuticals


Title: microRNA Fingerprints during Human Megakaryocytopoiesis

Patent Number: 8,865,885

Filed: June 25, 2013

Lead Inventor: Carlo Croce, Ohio State University


Title: Method for Downregulating Gene Expression in Fungi

Patent Number: 8,865,968

Filed: May 12, 2010

Lead Inventor: Marc Van De Craen, Devgen (Syngenta)

The Scan

Should've Been Spotted Sooner

Scientists tell the Guardian that SARS-CoV-2 testing issues at a UK lab should have been noticed earlier.

For Martian Fuel

Researchers have outlined a plan to produce rocket fuel on Mars that uses a combination of sunlight, carbon dioxide, frozen water, cyanobacteria, and engineered E. coli, according to Gizmodo.

To Boost Rapid Testing

The Washington Post writes that new US programs aim to boost the availability of rapid at-home SARS-CoV-2 tests.

PNAS Papers on Strawberry Evolution, Cell Cycle Regulators, False-Positive Triplex Gene Editing

In PNAS this week: strawberry pan-genome, cell cycle-related roles for MDM2 and MDMX, and more.