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IP Update: Recent Patents Awarded to Devgen, Alnylam, Alcon, and More


Title: Methods and Compositions for Increasing RNA Interference

Patent Number: 8,865,668

Filed: Feb. 20, 2009

Lead Inventor: Romaan Raemaekers, Devgen (Syngenta)

Title: RNAi-mediated Inhibition of TNA-alpha Signaling Pathway for Treatment of Glaucoma

Patent Number: 8,865,670

Filed: Feb. 10, 2011

Lead Inventor: Jon Chatterton, Alcon

Title: RNAi-mediated Inhibition of Spleen Tyrosine Kinase-related Inflammatory Conditions

Patent Number: 8,865,671

Filed: June 30, 2011

Lead Inventor: John Yanni, Alcon

Title: Compositions and Methods for Silencing Apolipoprotein B

Patent Number: 8,865,675

Filed: May 12, 2011

Lead Inventor: James Heyes, Protiva Biotherapeutics (Tekmira Pharmaceuticals)

Title: Methods and Kits for Synthesis of siRNA Expression Cassettes

Patent Number: 8,865,676

Filed: Jan. 31, 2013

Lead Inventor: John Rossi, City of Hope

Title: iRNA Agents with Biocleavable Tethers

Patent Number: 8,865,677

Filed: March 22, 2013

Lead Inventor: Muthiah Manoharan, Alnylam Pharmaceuticals

Title: microRNA Fingerprints during Human Megakaryocytopoiesis

Patent Number: 8,865,885

Filed: June 25, 2013

Lead Inventor: Carlo Croce, Ohio State University

Title: Method for Downregulating Gene Expression in Fungi

Patent Number: 8,865,968

Filed: May 12, 2010

Lead Inventor: Marc Van De Craen, Devgen (Syngenta)

The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.