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IP Update: Recent Patents Awarded to Devgen, Alnylam, Alcon, and More

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Title: Methods and Compositions for Increasing RNA Interference

Patent Number: 8,865,668

Filed: Feb. 20, 2009

Lead Inventor: Romaan Raemaekers, Devgen (Syngenta)


Title: RNAi-mediated Inhibition of TNA-alpha Signaling Pathway for Treatment of Glaucoma

Patent Number: 8,865,670

Filed: Feb. 10, 2011

Lead Inventor: Jon Chatterton, Alcon


Title: RNAi-mediated Inhibition of Spleen Tyrosine Kinase-related Inflammatory Conditions

Patent Number: 8,865,671

Filed: June 30, 2011

Lead Inventor: John Yanni, Alcon


Title: Compositions and Methods for Silencing Apolipoprotein B

Patent Number: 8,865,675

Filed: May 12, 2011

Lead Inventor: James Heyes, Protiva Biotherapeutics (Tekmira Pharmaceuticals)


Title: Methods and Kits for Synthesis of siRNA Expression Cassettes

Patent Number: 8,865,676

Filed: Jan. 31, 2013

Lead Inventor: John Rossi, City of Hope


Title: iRNA Agents with Biocleavable Tethers

Patent Number: 8,865,677

Filed: March 22, 2013

Lead Inventor: Muthiah Manoharan, Alnylam Pharmaceuticals


Title: microRNA Fingerprints during Human Megakaryocytopoiesis

Patent Number: 8,865,885

Filed: June 25, 2013

Lead Inventor: Carlo Croce, Ohio State University


Title: Method for Downregulating Gene Expression in Fungi

Patent Number: 8,865,968

Filed: May 12, 2010

Lead Inventor: Marc Van De Craen, Devgen (Syngenta)

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.