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IP Update: Recent Patents Awarded to CalTech, UMass, and More

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Title: Polyamides for Nucleic Acid Delivery

Patent Number: 8,685,368

Filed: July 3, 2012

Inventor: Theresa Reineke, Virginia Tech


Title: Regulation of Macrophage Activation using miR-125b

Patent Number: 8,685,727

Filed: June 18, 2012

Lead Inventor: Aadel Chaudhuri, California Institute of Technology


Title: Nucleic Acid Aptamers

Patent Number: 8,685,937

Filed: Feb. 18, 2010

Lead Inventor: Paloma Giangrande, University of Iowa


Title: Sequence-specific Inhibition of Small RNA Function

Patent Number: 8,685,946

Filed: Nov. 26, 2004

Lead Inventor: Gyorgy Hutvagner, University of Massachusetts

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.