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IP Update: Recent Patents Awarded to CalTech, UMass, and More


Title: Polyamides for Nucleic Acid Delivery

Patent Number: 8,685,368

Filed: July 3, 2012

Inventor: Theresa Reineke, Virginia Tech

Title: Regulation of Macrophage Activation using miR-125b

Patent Number: 8,685,727

Filed: June 18, 2012

Lead Inventor: Aadel Chaudhuri, California Institute of Technology

Title: Nucleic Acid Aptamers

Patent Number: 8,685,937

Filed: Feb. 18, 2010

Lead Inventor: Paloma Giangrande, University of Iowa

Title: Sequence-specific Inhibition of Small RNA Function

Patent Number: 8,685,946

Filed: Nov. 26, 2004

Lead Inventor: Gyorgy Hutvagner, University of Massachusetts

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.