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IP Update: Recent Patents Awarded to Arrowhead, City of Hope, and More

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Title: Polyconjugates for In Vivo Delivery of Polynucleotides

Patent Number: 8,658,211

Filed: Feb. 8, 2012

Lead Inventor: David Rozema, Arrowhead Research


Title: Methods and Compositions for the Specific Inhibition of Gene Expression by Double-stranded RNA

Patent Number: 8,658,356

Filed: June 3, 2011

Lead Inventor: John Rossi, City of Hope


Title: Methods for Diagnosing Colon Cancer using microRNAs

Patent Number: 8,658,362

Filed: Feb. 28, 2012

Lead Inventor: Carlo Croce, Ohio State University (Microlin Bio)


Title: microRNA-based Methods and Compositions for the Diagnosis, Prognosis, and Treatment of Breast Cancer

Patent Number: 8,658,370

Filed: Jan. 31, 2008

Lead Inventor: Carlo Croce, Ohio State University (Microlin Bio)


Title: siRNA Targeting Amyloid Beta (A4) Precursor Protein

Patent Number: 8,658,784

Filed: July 18, 2012

Lead Inventor: Anastasia Khvorova, Dharmacon (Thermo Fisher Scientific)


Title: siRNA Targeting Tie-2

Patent Number: 8,658,785

Filed: Oct. 9, 2012

Lead Inventor: Anastasia Khvorova, Dharmacon (Thermo Fisher Scientific)

The Scan

Support for Moderna Booster

An FDA advisory committee supports authorizing a booster for Moderna's SARS-CoV-2 vaccine, CNN reports.

Testing at UK Lab Suspended

SARS-CoV-2 testing at a UK lab has been suspended following a number of false negative results.

J&J CSO to Step Down

The Wall Street Journal reports that Paul Stoffels will be stepping down as chief scientific officer at Johnson & Johnson by the end of the year.

Science Papers Present Proteo-Genomic Map of Human Health, Brain Tumor Target, Tool to Infer CNVs

In Science this week: gene-protein-disease map, epigenomic and transcriptomic approach highlights potential therapeutic target for gliomas, and more