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IP Update: Recent Patents Awarded to Arrowhead, City of Hope, and More

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Title: Polyconjugates for In Vivo Delivery of Polynucleotides

Patent Number: 8,658,211

Filed: Feb. 8, 2012

Lead Inventor: David Rozema, Arrowhead Research


Title: Methods and Compositions for the Specific Inhibition of Gene Expression by Double-stranded RNA

Patent Number: 8,658,356

Filed: June 3, 2011

Lead Inventor: John Rossi, City of Hope


Title: Methods for Diagnosing Colon Cancer using microRNAs

Patent Number: 8,658,362

Filed: Feb. 28, 2012

Lead Inventor: Carlo Croce, Ohio State University (Microlin Bio)


Title: microRNA-based Methods and Compositions for the Diagnosis, Prognosis, and Treatment of Breast Cancer

Patent Number: 8,658,370

Filed: Jan. 31, 2008

Lead Inventor: Carlo Croce, Ohio State University (Microlin Bio)


Title: siRNA Targeting Amyloid Beta (A4) Precursor Protein

Patent Number: 8,658,784

Filed: July 18, 2012

Lead Inventor: Anastasia Khvorova, Dharmacon (Thermo Fisher Scientific)


Title: siRNA Targeting Tie-2

Patent Number: 8,658,785

Filed: Oct. 9, 2012

Lead Inventor: Anastasia Khvorova, Dharmacon (Thermo Fisher Scientific)

The Scan

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Viral Integration Study Critiqued

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Giraffe Species Debate

The Scientist reports that a new analysis aiming to end the discussion of how many giraffe species there are has only continued it.

Science Papers Examine Factors Shaping SARS-CoV-2 Spread, Give Insight Into Bacterial Evolution

In Science this week: genomic analysis points to role of human behavior in SARS-CoV-2 spread, and more.