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IP Update: Recent Patents Awarded to Alnylam, Tekmira, Polyplus, and More

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Title: RNA Interference Modulators of Hedgehog Signaling and Uses Thereof

Patent Number: 8,802,639

Filed: March 24, 2005

Inventor: David Bumcrot, Curis (Genentech)


Title: Oligonucleotides for RNA Interference and Biological Applications Thereof

Patent Number: 8,802,640

Filed: June 1, 2006

Lead Inventor: Jean-Paul Behr, Polyplus Transfection


Title: Lipid Formulation

Patent Number: 8,802,644

Filed: Jan. 25, 2012

Lead Inventor: Jianxin Chen, Tekmira Pharmaceuticals


Title: Amino Alcohol Cationic Lipids for Oligonucleotide Delivery

Patent Number: 8,802,863

Filed: Nov. 21, 2012

Lead Inventor: Brian Budzik, Sirna Therapeutics (Alnylam Pharmaceuticals)


Title: Methods and Compositions for Improved Delivery, Expression, or Activity of RNA Interference Agents

Patent Number: 8,802,138

Filed: April 11, 2012

Lead Inventor: Jessie Au, Optimum Therapeutics


Title: Gene Expression Signature for Classification of Tissue of Origin of Tumor Samples

Patent Number: 8,802,599

Filed: June 23, 2011

Lead Inventor: Ranit Aharonov, Rosetta Genomics


Title: In Vivo Polynucleotide Delivery Conjugates Having Enzyme-sensitive Linkages

Patent Number: 8,802,773

Filed: March 15, 2013

Lead Inventor: David Rozema, Arrowhead Research


Title: miR-164 Gene That Controls Plant Root System Development and Fertility and Use Thereof

Patent Number: 8,802,929

Filed: Jan. 3, 2012

Lead Inventor: Lizhong Xiong, Huazhong Agricultural University

The Scan

NFTs for Genome Sharing

Nature News writes that non-fungible tokens could be a way for people to profit from sharing genomic data.

Wastewater Warning System

Time magazine writes that cities and college campuses are monitoring sewage for SARS-CoV-2, an approach officials hope lasts beyond COVID-19.

Networks to Boost Surveillance

Scientific American writes that new organizations and networks aim to improve the ability of developing countries to conduct SARS-CoV-2 genomic surveillance.

Genome Biology Papers on Gastric Cancer Epimutations, BUTTERFLY, GUNC Tool

In Genome Biology this week: recurrent epigenetic mutations in gastric cancer, correction tool for unique molecular identifier-based assays, and more.