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IP Update: Recent Patents Awarded to Alnylam, Senesco, Alcon, and More

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Title: Inhibition of Apoptosis-specific eFI-5A with Antisense Oligonucleotides and siRNA as Anti-inflammatory Therapeutics

Patent Number: 8,754,057

Filed: May 2, 2011

Lead Inventor: John Thompson, Senesco Technologies


Title: Use of miR-30e to Treat Vascular Lesions

Patent Number: 8,754,059

Filed: Aug. 25, 2011

Inventor: Lina Shehadeh, University of Miami


Title: Therapeutic Compositions

Patent Number: 8,754,201

Filed: March 10, 2010

Inventor: Muthiah Manoharan, Alnylam Pharmaceuticals


Title: RNAi-related Inhibition of TNF-alpha Signaling Pathway for Treatment of Ocular Angiogenesis

Patent Number: 8,754,202

Filed: June 27, 2011

Inventor: Jon Chatterton, Alcon


Title: Human microRNAs and Methods for Inhibiting Same

Patent Number: 8,754,203

Filed: May 11, 2012

Lead Inventor: Thomas Tuschl, Rockefeller University

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.