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IP Update: Recent Patents Awarded to Alnylam, RXi, IBM, and More


Title: Sustained-release Nucleic Acid Matrix Compositions

Patent Number: 8,795,726

Filed: Jan. 18, 2011

Lead Inventor: Noam Emanuel, Polypid

Title: Hydrophobic Nanotubes and Nanoparticles as Transporters for the Delivery of Drugs into Cells

Patent Number: 8,795,734

Filed: Aug. 3, 2012

Lead Inventor: Hongjie Dai, Stanford University

Title: Ribonucleic Acid Interference Molecules of Oryza sativa

Patent Number: 8,795,987

Filed: July 31, 2008

Lead Inventor: Tien Huynh, IBM

Title: Primer Extension-based Method for the Generation of siRNA/miRNA Expression Vectors

Patent Number: 8,795,988

Filed: Aug. 15, 2008

Lead Inventor: Lin Liu, Oklahoma State University

Title: RNA Interference-mediating Small RNA Molecules

Patent Number: 8,796,016

Filed: June 21, 2010

Lead Inventor: Thomas Tuschl, Max Planck Institute

Title: Methods for Attenuating Dengue Virus Infection

Patent Number: 8,796,235

Filed: Sept. 10, 2004

Lead Inventor: Shyam Mohapatra, University of South Florida

Title: Short RNA Mimetics

Patent Number: 8,796,238

Filed: Sept. 13, 2010

Inventor: Kevin Forbes, Sigma-Aldrich

Title: siRNA Compounds Comprising Terminal Substitutions

Patent Number: 8,796,239

Filed: Nov. 25, 2010

Inventor: Sharon Avkin-Nachum, Quark Pharmaceuticals

Title: Modified iRNA Agents

Patent Number: 8,796,436

Filed: March 22, 2013

Lead Inventor: Muthiah Manoharan, Alnylam Pharmaceuticals

Title: Combined Hairpin-Antisense Compounds and Methods for Modulating Expression

Patent Number: 8,796,442

Filed: March 20, 2008

Lead Inventor: John Shanklin, Brookhaven National Laboratory

Title: Reduced-size Self-delivering RNAi Compounds

Patent Number: 8,796,443

Filed: Sept. 22, 2009

Lead Inventor: Anastasia Khvorova, RXi Pharmaceuticals

Title: Methods and Compositions for the Specific Inhibition of Gene Expression by Double-stranded RNA

Patent Number: 8,796,444

Filed: July 6, 2011

Lead Inventor: John Rossi, City of Hope

The Scan

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.

Algorithm Teases Out Genetic Ancestry in Individuals at Biobank Scale

Researchers develop an algorithm known as Rye to tease apart ancestry fractions in admixed individuals at a biobank-scale, applying it to 488,221 UK Biobank participants in Nucleic Acids Research.

Multi-Ancestry Analysis Highlights Comparable Common Variants at Complex Trait-Linked Loci

Researchers in Nature Genetics examine common variants implicated in more than three dozen conditions, estimating genetic effect similarities across ancestry tracts in admixed individuals.

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.