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IP Update: Recent Patents Awarded to Alnylam, RXi, IBM, and More

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Title: Sustained-release Nucleic Acid Matrix Compositions

Patent Number: 8,795,726

Filed: Jan. 18, 2011

Lead Inventor: Noam Emanuel, Polypid


Title: Hydrophobic Nanotubes and Nanoparticles as Transporters for the Delivery of Drugs into Cells

Patent Number: 8,795,734

Filed: Aug. 3, 2012

Lead Inventor: Hongjie Dai, Stanford University


Title: Ribonucleic Acid Interference Molecules of Oryza sativa

Patent Number: 8,795,987

Filed: July 31, 2008

Lead Inventor: Tien Huynh, IBM


Title: Primer Extension-based Method for the Generation of siRNA/miRNA Expression Vectors

Patent Number: 8,795,988

Filed: Aug. 15, 2008

Lead Inventor: Lin Liu, Oklahoma State University


Title: RNA Interference-mediating Small RNA Molecules

Patent Number: 8,796,016

Filed: June 21, 2010

Lead Inventor: Thomas Tuschl, Max Planck Institute


Title: Methods for Attenuating Dengue Virus Infection

Patent Number: 8,796,235

Filed: Sept. 10, 2004

Lead Inventor: Shyam Mohapatra, University of South Florida


Title: Short RNA Mimetics

Patent Number: 8,796,238

Filed: Sept. 13, 2010

Inventor: Kevin Forbes, Sigma-Aldrich


Title: siRNA Compounds Comprising Terminal Substitutions

Patent Number: 8,796,239

Filed: Nov. 25, 2010

Inventor: Sharon Avkin-Nachum, Quark Pharmaceuticals


Title: Modified iRNA Agents

Patent Number: 8,796,436

Filed: March 22, 2013

Lead Inventor: Muthiah Manoharan, Alnylam Pharmaceuticals


Title: Combined Hairpin-Antisense Compounds and Methods for Modulating Expression

Patent Number: 8,796,442

Filed: March 20, 2008

Lead Inventor: John Shanklin, Brookhaven National Laboratory


Title: Reduced-size Self-delivering RNAi Compounds

Patent Number: 8,796,443

Filed: Sept. 22, 2009

Lead Inventor: Anastasia Khvorova, RXi Pharmaceuticals


Title: Methods and Compositions for the Specific Inhibition of Gene Expression by Double-stranded RNA

Patent Number: 8,796,444

Filed: July 6, 2011

Lead Inventor: John Rossi, City of Hope

The Scan

Steps for Quick Review

The US Food and Drug Administration is preparing for the quick review of drugs and vaccines for the Omicron variant, according to the Wall Street Journal.

Moving Away From Using Term 'Race'

A new analysis finds that geneticists are using the term "race" in their papers less than in years past, as Science reports.

Point of the Program

The Guardian writes that some scientists have called the design of a UK newborn sequencing program into question.

Science Papers Present Multi-Omic Analysis of Lung Cells, Regulation of Cardiomyocyte Proliferation

In Science this week: a multi-omic analysis of lung cells focuses on RIT1-regulated pathways, and more.