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IP Update: Recent Patents Awarded to Alnylam, Quark, Qiagen, and More

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Title: RNA Interference-mediating Small RNA Molecules

Patent Number: 8,853,384

Filed: Dec. 2, 2009

Lead Inventor: Thomas Tuschl, Max Planck Institute


Title: Transgenic Plant-based Methods for Plant Pests Using RNAi

Patent Number: 8,853,489

Filed: Sept.18, 2006

Lead Inventor: Romaan Raemaekers, Devgen (Syngenta)


Title: Lipid-formulated Compositions and Methods for Inhibiting Expression of Eg5 and VEGF Genes

Patent Number: 8,859,516

Filed: Sept.10, 2010

Lead Inventor: David Bumcrot, Alnylam Pharmaceuticals


Title: Methods Targeting miR-33 microRNAs for Regulating Lipid Metabolism

Patent Number: 8,859,519

Filed: Aug. 25, 2011

Inventor: Anders Naar, Harvard Medical School


Title: Oligomeric Compounds and Compositions for Use in Modulation of Small, Non-coding RNAs

Patent Number: 8,859,521

Filed: Dec. 30, 2013

Lead Inventor: Frank Bennett, Regulus Therapeutics


Title: Use of RNAi Inhibiting PARP Activity for the Manufacture of a Medicament for the Treatment of Cancer

Patent Number: 8,859,562

Filed: Sept. 15, 2006

Inventor: Thomas Helleday, University of Sheffield


Title: Modified Short Interfering RNA

Patent Number: 8,859,749

Filed: March 8, 2006

Lead Inventor: Ioanna Andreou, Qiagen


Title: RNAi Modulation of RSV and Therapeutic Uses Thereof

Patent Number: 8,859,750

Filed: March 29, 2012

Lead Inventor: Rachel Meyers, Alnylam Pharmaceuticals


Title: Oligonucleotide Compounds Comprising Non-nucleotide Overhangs

Patent Number: 8,859,751

Filed: Jan. 6, 2012

Lead Inventor: Sharon Nachum, Quark Pharmaceuticals


Title: siRNA-based Therapy of Fibrodysplasia Ossificans Progressiva

Patent Number: 8,859,752

Filed: Oct. 17, 2012

Lead Inventor: Frederick Kaplan, University of Pennsylvania

The Scan

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.

Seagull Microbiome Altered by Microplastic Exposure

The overall diversity and the composition at gut microbiome sites appear to coincide with microplastic exposure and ingestion in two wild bird species, according to a new Nature Ecology and Evolution study.

Study Traces Bladder Cancer Risk Contributors in Organ Transplant Recipients

In eLife, genome and transcriptome sequencing reveal mutation signatures, recurrent somatic mutations, and risky virus sequences in bladder cancers occurring in transplant recipients.

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.