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IP Update: Recent Patents Awarded to Alnylam Pharmaceuticals, Marina Biotech, and More

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Title: Methods and Means for Producing Efficient Silencing Construct Using Recombinatorial Cloning

Patent Number: 8,877,435

Filed: Sept. 21, 2010

Lead Inventor: Christopher Helliwell, Commonwealth Scientific and Industrial Research Organization


Title: Method for Rapidly Evaluating Performance of Short Interfering RNA with Novel Chemical Modifications

Patent Number: 8,877,439

Filed: Dec. 9, 2010

Lead Inventor: Gabor Butora, Sirna Therapeutics (Alnylam Pharmaceuticals)


Title: Compositions for Inhibiting Gene Expression and Uses Thereof

Patent Number: 8,877,722

Filed: March 25, 2011

Lead Inventor: Sudhir Agrawal, Idera Pharmaceuticals


Title: Method and Medicament for Inhibiting the Expression of a Given Gene

Patent Number: 8,877,726

Filed: Oct. 19, 2012

Lead Inventor: Roland Kreutzer, Alnylam Pharmaceuticals


Title: Delivery of dsRNA to Arthropods

Patent Number: 8,877,727

Filed: April 5, 2013

Lead Inventor: Steven Whyard, Commonwealth Scientific and Industrial Research Organization


Title: Amino Acid Lipids and Uses Thereof

Patent Number: 8,877,729

Filed: July 1, 2013

Lead Inventor: Steven Quay, Marina Biotech


Title: Glycoconjugates of RNA Interference Agents

Patent Number: 8,877,917

Filed: April 23, 2008

Lead Inventor: Andrea Forst, Alnylam Pharmaceuticals

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.