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IP Update: Recent Patents Awarded to Alnylam, MIT, Institute for Systems Biology, and More


Title: microRNA-based Methods and Compositions for the Diagnosis, Prognosis, and Treatment of Tumor Involving Chromosomal Rearrangements

Patent Number: 8,828,656

Filed: July 31, 2012

Lead Inventor: Joern Bullerdiek, University of Bremen

Title: Carbohydrate Conjugates as Delivery Agents for Oligonucleotides

Patent Number: 8,828,956

Filed: Dec. 4, 2012

Lead Inventor: Muthiah Manoharan, Alnylam Pharmaceuticals

Title: Methods and Compositions to Protect Aquatic Invertebrates from Disease

Patent Number: 8,828,961

Filed: Oct. 19, 2011

Lead Inventor: John Loy, Harrisvaccines

Title: siRNA Compositions and Methods for Potently Inhibiting Viral Infections

Patent Number: 8,828,962

Filed: Dec. 12, 2011

Lead Inventor: Bojian Zheng, Xiangxue Group

Title: Diagnosis and Treatment of Chronic Lymphocytic Leukemia

Patent Number: 8,828,963

Filed: March 16, 2012

Lead Inventor: David Galas, Institute for Systems Biology

Title: miR-150 for the Treatment of Blood Disorders

Patent Number: 8,828,965

Filed: Aug. 21, 2013

Lead Inventor: Jun Lu, Massachusetts Institute of Technology (Dana-Farber Cancer Institute)

Title: Immuno-RNA Constructs

Patent Number: 8,829,178

Filed: Dec. 21, 2006

Lead Inventor: Stefan Barth, Fraunhofer

Title: Means for Inhibiting the Expression of ANG2

Patent Number: 8,829,179

Filed: Feb. 18, 2010

Lead Inventor: Ansgar Santel, Silence Therapeutics

Title: Methods and Compositions for RNA Interference

Patent Number: 8,829,264

Filed: June 18, 2012

Lead Inventor: Gergory Hannon, Cold Spring Harbor Laboratory

The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.