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IP Update: Recent Patents Awarded to Alnylam, Merck, Alcon

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Title: Hepatitis C dsRNA Effector Molecules, Expression Constructs, Compositions, and Methods of Use

Patent Number: 8,614,198

Filed: June 28, 2008

Lead Inventor: Daniel McCallus, Alnylam Pharmaceuticals


Title: Double-stranded RNA Director to CASP2 and Methods of Use Thereof

Patent Number: 8,614,309

Filed: Sept. 4, 2008

Lead Inventor: Elena Feinstein, Quark Pharmaceuticals


Title: Devices, Systems, and Methods for Improving Memory and/or Cognitive Function through Brain Delivery of siRNA

Patent Number: 8,618,069

Filed: Oct. 8, 2009

Lead Inventor: William Kaemmerer, Medtronic


Title: RNA Interference-mediated Inhibition of Gene Expression using Chemically Modified Short Interfering Nucleic Acid

Patent Number: 8,618,277

Filed: May 25, 2012

Lead Inventor: Leonid Beigelman, Merck


Title: RNAi-mediated Inhibition of Histamine Receptor H1-related Conditions

Patent Number: 8,618,278

Filed: June 11, 2012

Lead Inventor: John Yanni, Alcon

The Scan

Support for Moderna Booster

An FDA advisory committee supports authorizing a booster for Moderna's SARS-CoV-2 vaccine, CNN reports.

Testing at UK Lab Suspended

SARS-CoV-2 testing at a UK lab has been suspended following a number of false negative results.

J&J CSO to Step Down

The Wall Street Journal reports that Paul Stoffels will be stepping down as chief scientific officer at Johnson & Johnson by the end of the year.

Science Papers Present Proteo-Genomic Map of Human Health, Brain Tumor Target, Tool to Infer CNVs

In Science this week: gene-protein-disease map, epigenomic and transcriptomic approach highlights potential therapeutic target for gliomas, and more