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IP Update: Recent Patents Awarded to Alnylam, Life Tech, and More

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Title: Methods for Normalizing and for Identifying Small Nucleic Acids

Patent Number: 8,741,569

Filed: Oct. 23, 2009

Lead Inventor: Kai Lao, Applied Biosystems (Life Technologies)


Title: PHD2 Inhibition for Blood Vessel Normalization and Uses Thereof

Patent Number: 8,741,862

Filed: Jan. 20, 2010

Lead Inventor: Peter Carmeliet, Life Science Research Partners


Title: Compositions and Methods for Inhibiting Expression of Transthyretin

Patent Number: 8,741,866

Filed: March 1, 2012

Lead Inventor: Dinah Sah, Alnylam Pharmaceuticals


Title: RNA Sequence-specific Mediators of RNA Interference

Patent Number: 8,742,092

Filed: March 1, 2012

Lead Inventor: Thomas Tuschl, Max Planck Institute


Title: Methods of Novel Therapeutic Candidate Identification through Gene Expression Analysis in Vascular-related Diseases

Patent Number: 8,741,861

Filed: March 27, 2009

Inventor: David Mann, Vascular Biosciences


Title: Panel of microRNAs that Silence the MCL-1 Gene and Sensitize Cancer Cells to ABT-263

Patent Number: 8,742,083

Filed: Dec. 23, 2010

Lead Inventor: Dimitri Semizarov, AbbVie

The Scan

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.

Seagull Microbiome Altered by Microplastic Exposure

The overall diversity and the composition at gut microbiome sites appear to coincide with microplastic exposure and ingestion in two wild bird species, according to a new Nature Ecology and Evolution study.

Study Traces Bladder Cancer Risk Contributors in Organ Transplant Recipients

In eLife, genome and transcriptome sequencing reveal mutation signatures, recurrent somatic mutations, and risky virus sequences in bladder cancers occurring in transplant recipients.

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.