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IP Update: Recent Patents Awarded to Alnylam, GE Healthcare, Sanofi, and More

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Title: Treatment of Cancer by Inhibition of IGFBPs and Clusterin

Patent Number: 8,835,401

Filed: May 29, 2013

Inventor: Martin Gleave, University of British Columbia


Title: Expression Cassettes for Seed-specific Expression in Plants

Patent Number: 8,835,622

Filed: Nov. 25, 2009

Lead Inventor: Franck Pinot, Bayer BioScience


Title: RNA Interference-mediated Inhibition of Catenin Beta 1 Gene Expression Using Short Interfering Nucleic Acid

Patent Number: 8,835,623

Filed: Aug. 6, 2013

Lead Inventor: Duncan Brown, Sirna Therapeutics (Alnylam Pharmaceuticals)


Title: microRNA Scaffolds, Non-naturally Occurring microRNAs, and Methods for Optimizing Non-naturally Occurring microRNAs

Patent Number: 8,841,267

Filed: May 22, 2008

Lead Inventor: Melissa Kelley, Dharmacon (GE Healthcare)


Title: Polynucleotides for Use in Treating and Diagnosing Cancers

Patent Number: 8,841,269

Filed: Feb. 23, 2011

Inventor: Gary Xiao, Creighton University


Title: Use of Inhibitors of Zdhhc2 Activity for Modulation of Adipogenesis

Patent Number: 8,841,270

Filed: May 19, 2010

Lead Inventor: Diana Hall, Sanofi


Title: Double-stranded RNA-based Nanoparticles for Insect Gene Silencing

Patent Number: 8,841,272

Filed: May 31, 2012

Lead Inventor: Kun Yan Zhu, Kansas State University


Title: Precursor miRNA Loop-modulated Target Regulation

Patent Number: 8,841,437

Filed: May 28, 2010

Lead Inventor: Chang-Zheng Chen, Stanford University

The Scan

Guidelines for Ancient DNA Work

More than two dozen researchers have developed new ethical guidelines for conducting ancient DNA research, which they present in Nature.

And Cleared

A UK regulator has cleared former UK Prime Minister David Cameron in concerns he should have registered as a consultant-lobbyist for his work with Illumina, according to the Financial Times.

Suit Over Allegations

The Boston Globe reports that David Sabatini, who was placed on leave from MIT after allegations of sexual harassment, is suing his accuser, the Whitehead Institute, and the institute's director.

Nature Papers on Esophageal Cancer, Origin of Modern Horses, Exome Sequencing of UK Biobank Participants

In Nature this week: genetic and environmental influences of esophageal cancer, domestic horse origin traced to Western Eurasian steppes, and more.