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IP Update: Recent Patents Awarded to Alnylam, Baxter, GE Healthcare, and More

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Title: Nucleic Acid Microparticles for Pulmonary Delivery

Patent Number: 8,808,747

Filed: April 17, 2008

Inventor: Larry Brown, Baxter Healthcare


Title: shRNA Molecules and Methods of Use Thereof

Patent Number: 8,808,983

Filed: June 29, 2012

Inventor: Donald Rao, Gradalis


Title: Compositions and Methods for Altering Wnt Autocrine Signaling

Patent Number: 8,809,287

Filed: Nov. 15, 2005

Lead Inventor: Anna Bafico, Mount Sinai


Title: Double-stranded Nucleic Acid Molecule, Cancer Cell Proliferation Inhibitor, and Pharmaceutical Agent Suitable for Prevention or Treatment of Cancer

Patent Number: 8,809,289

Filed: Sept. 10, 2010

Lead Inventor: Satoshi Inoue, Saitama Medical University (RNAi Co.)


Title: Compositions and Methods for Inhibiting Expression of the PCSK9 Gene

Patent Number: 8,809,292

Filed: May 15, 2012

Lead Inventor: Pamela Tan, Alnylam Pharmaceuticals


Title: Compositions and Methods for Inhibiting Gene Expression of Hepatitis B Virus

Patent Number: 8,809,293

Filed: June 28, 2012

Lead Inventor: Daniel Chin, Arrowhead Research


Title: Method of Inhibiting miR-33 Using a Modified Oligo Nucleotide

Patent Number: 8,809,294

Filed: July 2, 2012

Lead Inventor: Christine Esau, Regulus Therapeutics


Title: Tripartite Oligonucleotide Complexes and Methods for Gene Silencing by RNA Interference

Patent Number: 8,809,514

Filed: Sept. 20, 2007

Lead Inventor: Christina Yamada, GE Healthcare (Dharmacon)


Title: Methods and Compositions for the Specific Inhibition of Gene Expression by Double-stranded RNA

Patent Number: 8,809,515

Filed: July 8, 2011

Lead Inventor: John Rossi, City of Hope


Title: Therapeutic Compositions

Patent Number: 8,809,516

Filed: Sept. 25, 2012

Lead Inventor: Muthiah Manoharan, Alnylam Pharmaceuticals


Title: Method of Inhibiting Alu RNA and Therapeutic Uses Thereof

Patent Number: 8,809,517

Filed: June 1, 2011

Inventor: Jayakrishna Ambati, University of Kentucky

The Scan

Steps for Quick Review

The US Food and Drug Administration is preparing for the quick review of drugs and vaccines for the Omicron variant, according to the Wall Street Journal.

Moving Away From Using Term 'Race'

A new analysis finds that geneticists are using the term "race" in their papers less than in years past, as Science reports.

Point of the Program

The Guardian writes that some scientists have called the design of a UK newborn sequencing program into question.

Science Papers Present Multi-Omic Analysis of Lung Cells, Regulation of Cardiomyocyte Proliferation

In Science this week: a multi-omic analysis of lung cells focuses on RIT1-regulated pathways, and more.