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IP Update: Recent Patents Awarded to Alnylam, Baxter, GE Healthcare, and More

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Title: Nucleic Acid Microparticles for Pulmonary Delivery

Patent Number: 8,808,747

Filed: April 17, 2008

Inventor: Larry Brown, Baxter Healthcare


Title: shRNA Molecules and Methods of Use Thereof

Patent Number: 8,808,983

Filed: June 29, 2012

Inventor: Donald Rao, Gradalis


Title: Compositions and Methods for Altering Wnt Autocrine Signaling

Patent Number: 8,809,287

Filed: Nov. 15, 2005

Lead Inventor: Anna Bafico, Mount Sinai


Title: Double-stranded Nucleic Acid Molecule, Cancer Cell Proliferation Inhibitor, and Pharmaceutical Agent Suitable for Prevention or Treatment of Cancer

Patent Number: 8,809,289

Filed: Sept. 10, 2010

Lead Inventor: Satoshi Inoue, Saitama Medical University (RNAi Co.)


Title: Compositions and Methods for Inhibiting Expression of the PCSK9 Gene

Patent Number: 8,809,292

Filed: May 15, 2012

Lead Inventor: Pamela Tan, Alnylam Pharmaceuticals


Title: Compositions and Methods for Inhibiting Gene Expression of Hepatitis B Virus

Patent Number: 8,809,293

Filed: June 28, 2012

Lead Inventor: Daniel Chin, Arrowhead Research


Title: Method of Inhibiting miR-33 Using a Modified Oligo Nucleotide

Patent Number: 8,809,294

Filed: July 2, 2012

Lead Inventor: Christine Esau, Regulus Therapeutics


Title: Tripartite Oligonucleotide Complexes and Methods for Gene Silencing by RNA Interference

Patent Number: 8,809,514

Filed: Sept. 20, 2007

Lead Inventor: Christina Yamada, GE Healthcare (Dharmacon)


Title: Methods and Compositions for the Specific Inhibition of Gene Expression by Double-stranded RNA

Patent Number: 8,809,515

Filed: July 8, 2011

Lead Inventor: John Rossi, City of Hope


Title: Therapeutic Compositions

Patent Number: 8,809,516

Filed: Sept. 25, 2012

Lead Inventor: Muthiah Manoharan, Alnylam Pharmaceuticals


Title: Method of Inhibiting Alu RNA and Therapeutic Uses Thereof

Patent Number: 8,809,517

Filed: June 1, 2011

Inventor: Jayakrishna Ambati, University of Kentucky

The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.