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IP Update: Recent Patents Awarded to Alnylam, Baxter, GE Healthcare, and More


Title: Nucleic Acid Microparticles for Pulmonary Delivery

Patent Number: 8,808,747

Filed: April 17, 2008

Inventor: Larry Brown, Baxter Healthcare

Title: shRNA Molecules and Methods of Use Thereof

Patent Number: 8,808,983

Filed: June 29, 2012

Inventor: Donald Rao, Gradalis

Title: Compositions and Methods for Altering Wnt Autocrine Signaling

Patent Number: 8,809,287

Filed: Nov. 15, 2005

Lead Inventor: Anna Bafico, Mount Sinai

Title: Double-stranded Nucleic Acid Molecule, Cancer Cell Proliferation Inhibitor, and Pharmaceutical Agent Suitable for Prevention or Treatment of Cancer

Patent Number: 8,809,289

Filed: Sept. 10, 2010

Lead Inventor: Satoshi Inoue, Saitama Medical University (RNAi Co.)

Title: Compositions and Methods for Inhibiting Expression of the PCSK9 Gene

Patent Number: 8,809,292

Filed: May 15, 2012

Lead Inventor: Pamela Tan, Alnylam Pharmaceuticals

Title: Compositions and Methods for Inhibiting Gene Expression of Hepatitis B Virus

Patent Number: 8,809,293

Filed: June 28, 2012

Lead Inventor: Daniel Chin, Arrowhead Research

Title: Method of Inhibiting miR-33 Using a Modified Oligo Nucleotide

Patent Number: 8,809,294

Filed: July 2, 2012

Lead Inventor: Christine Esau, Regulus Therapeutics

Title: Tripartite Oligonucleotide Complexes and Methods for Gene Silencing by RNA Interference

Patent Number: 8,809,514

Filed: Sept. 20, 2007

Lead Inventor: Christina Yamada, GE Healthcare (Dharmacon)

Title: Methods and Compositions for the Specific Inhibition of Gene Expression by Double-stranded RNA

Patent Number: 8,809,515

Filed: July 8, 2011

Lead Inventor: John Rossi, City of Hope

Title: Therapeutic Compositions

Patent Number: 8,809,516

Filed: Sept. 25, 2012

Lead Inventor: Muthiah Manoharan, Alnylam Pharmaceuticals

Title: Method of Inhibiting Alu RNA and Therapeutic Uses Thereof

Patent Number: 8,809,517

Filed: June 1, 2011

Inventor: Jayakrishna Ambati, University of Kentucky

The Scan

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.

Algorithm Teases Out Genetic Ancestry in Individuals at Biobank Scale

Researchers develop an algorithm known as Rye to tease apart ancestry fractions in admixed individuals at a biobank-scale, applying it to 488,221 UK Biobank participants in Nucleic Acids Research.

Multi-Ancestry Analysis Highlights Comparable Common Variants at Complex Trait-Linked Loci

Researchers in Nature Genetics examine common variants implicated in more than three dozen conditions, estimating genetic effect similarities across ancestry tracts in admixed individuals.

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.