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Title: RNA Interference Agents for Therapeutic Use

Patent Number: 7,951,784

Filed: Jan. 26, 2007

Lead Inventor: Tariq Rana, University of Massachusetts (RXi Pharmaceuticals)

“The invention features chemically modified small interfering RNAs that are stable in vivo and retain the ability to form an A-form helix when in association with a target RNA,” the patent's abstract states. “The featured siRNA are effective therapeutics, particularly for targeting SOD1.”

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