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Intradigm, MIT, Alnylam, UK Patent Office

Intradigm Licenses Nucleic Acid Delivery IP from MIT
Intradigm said this week that it has licensed rights to a nucleic acid delivery patent from the Massachusetts Institute of Technology for use in RNAi drug development.
The company said the IP it has licensed covers a broad range of biodegradable polymer structures that are used in delivering RNAi-based therapeutics. It added that the license would enable it to pursue applications for its NanoPlex delivery technology across a broader range of therapeutic indications.
Intradigm’s RNAi Nanoplex technology is made of an active siRNA molecule and a biodegradable polycationic polymer.
Financial terms of the agreement were not released.

Alnylam Issued UK Patent on siRNA Composition, Methods
Alnylam Pharmaceuticals this week announced that it has received a patent from the United Kingdom Patent Office covering compositions and methods, including pharmaceutical compositions, for small interfering RNAs.
The patent, No. UK 2417727, is entitled "Double-stranded Ribonucleic Acid with Increased Effectiveness in an Organism." The company said the IP specifically claims siRNA molecules of any length that contain overhangs and blunt ends, including siRNAs containing chemical modifications and certain novel motifs.

The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.