Bioinformatics has been a relative latecomer to the RNA interference party. The same qualities that have made RNAi so popular for functional genomics research — its ease of use, its reproducibility, and its effectiveness — make clever algorithms and computational tricks pretty much irrelevant.

Armed with GenBank and a few simple guidelines provided by RNAi pioneer Tom Tuschl of Rockefeller University, anyone can design a 21-nucleotide siRNA sequence with a 70 percent chance of silencing a gene of interest by destroying mRNA during translation.

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.