About two years ago, John Kim, a postdoctoral fellow in the lab of Gary Ruvkun at Harvard Medical School, was looking for a better way to study RNAi on a genome-wide level. What he came up with was a novel method of applying RNAi to RNAi.
Together with colleagues including Harrison Gabel and Ravi Kamath, he used this approach to screen the C. elegans genome to find genes required for RNAi. The results of their work were published last week in Science.
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