Gradalis Pushes Back shRNA Rx Trial to Evaluate Delivery, Expression Tech | GenomeWeb

Although it had expected to begin phase I testing of its lead expressed RNAi cancer drug last month, Gradalis pushed back the clinical trial in order to test the non-RNAi components of the therapy separately in humans first, a company official told RNAi News this week.

Gradalis now plans to file an investigational new drug application for the treatment later this year, and expects the added work that delayed the phase I trial will have laid the groundwork for more rapidly moving follow-on drugs into clinical studies.

Get the full story with
GenomeWeb Premium

Only $95 for the
first 90 days*

A trial upgrade to GenomeWeb Premium gives you full site access, interest-based email alerts, access to archives, and more. Never miss another important industry story.

Try GenomeWeb Premium now.

Already a GenomeWeb Premium member? Login Now.
Or, See if your institution qualifies for premium access.

*Before your trial expires, we’ll put together a custom quote with your long-term premium options.

Not ready for premium?

Register for Free Content
You can still register for access to our free content.

Biomedical research projects are generating a ton of data that still needs to be analyzed, NPR reports.

Theranos is retiring some of its board members, including Henry Kissinger and George Shultz, Business Insider reports.

The heads of 29 scientific societies and some 2,300 researchers call on President-elect Donald Trump to rely on and support science in two separate letters.

In Science this week: genetically modified flu virus could be key to new live vaccines, and more.