Title: Nucleozymes. Number: 6,713,456. Filed: June, 2, 1995. Lead Inventor: Nassim Usman, Massachusetts Institute of Technology.
The invention comprises “nucleozymes containing ribonucleotides and deoxyribonucleotides, or nucleic acid analogues,” according to the patent’s abstract. “Nucleozymes have catalytic activity and are significantly more resistant to degradation than their all-RNA ribozyme counterparts.”