The US Food and Drug Administration has approved Tekmira Pharamceuticals' investigational new drug application for its siRNA-based hypercholesterolemia drug ApoB SNALP, the company said this week.

The drug targets apolipoprotein B, a protein involved in cholesterol metabolism. In the planned phase I study, escalating doses of ApoB SNALP will be examine for safety, tolerability, and pharmacokinetics in about 30 adults with elevated low-density lipoprotein cholesterol, according to the company.

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The apple has traveled westward and eastward along the Silk Road, according to a new genetic analysis.

In Nature this week: GWAS data used to reposition drugs for psychiatric use, and more.

Genetic disease risk information doesn't always spur people to make healthy lifestyle changes, according to the Associated Press.

A University of California, San Diego-led team has used liquid biopsies to uncover possible treatments for patients with cancers of unknown primary.

Sep
12
Sponsored by
PerkinElmer

This webinar will cover recent advances in the use of CRISPR for generating animal models and cell lines.