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Enzo Life Sciences Amplification Method and Ambion s Anti-miR and Pre-miR


Enzo Biochem said last week that its subsidiary, Enzo Life Sciences, has launched a new amplification method for improving gene-expression data from microarray experiments.

According to the company, the method is able to amplify either the antisense or sense strand of RNA, and will be marketed in various formats.

The first product amplifies the antisense strand of RNA.

Ambion has recently introduced Anti-miR microRNA inhibitors.

The inhibitors are chemically modified and optimized nucleic acids designed to specifically target the miRNA molecules in cells, said the company. The inhibitors allow for the specific control of miRNA activity, the regulation of miRNA cellular levels, and can be used in experiments including miRNA target site identification and validation, it added.

Specific details about the inhibitors can be found at

Ambion has also recently launched Pre-miR miRNA precursor molecules.

The company said these molecules are chemically modified nucleic acids designed to mimic miRNA molecules in cells.

“The Pre-miR miRNA precursor molecules are designed to directly enter into the miRNA processing pathway, and are treated identically to endogenous miRNA within the cell,” said Ambion. Therefore, they avoid any non-miRNA cellular response seen with siRNA-like designs, the company added.

Specific details about these molecules can be found at

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.