Skip to main content
Premium Trial:

Request an Annual Quote

EGEN microRNA Inhibitor Shows Promise in Preclinical Testing

Premium

EGEN announced this week that its microRNA inhibitor-based treatment for pulmonary arterial hypertension was able to reverse the pulmonary hypertension associated with advanced stages of the disease and restore cardiovascular function in rat models.

According to the company, the drug targets miR-145, which has been linked to vascular remodeling in PAH, and is delivered with a propriatry mPEG nanoparticle that is administered directly to the lung.

EGEN is also developing RNAi-based drugs with a focus on cancer (GSN 8/5/2010).

The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.