As the development of RNAi-based therapeutics has advanced during 2013, each of the major publically traded companies in the field has seen significant increases in both stock price and, more importantly, market capitalization.

Although there have been gains made in terms of the basic science behind the gene-silencing technology during the year, it is RNAi's translation from a genomics research tool into a clinical-stage therapeutic modality that has driven Wall Street's interest.

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