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Dharmacon s siGenome, Qiagen s 2-for-Silencing, Ambion s mirVana, Nature Reviews Genetics, and Arkitek Studios

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Dharmacon announced this week that it has released its siGenome siRNA collection.

The collection, said the company, includes Smartpool siRNA reagents and individual Smartselection-designed siRNA duplexes targeting more than 22,000 human genes in the NCBI RefSeq database.

Details about the siGenome collection can be found at http://www.dharmacon.com.


Qiagen announced this week the introduction of 2-for-Silencing siRNA duplexes.

The product, said the company, consists of two siRNA duplexes that have been custom designed to target a gene of choice. Qiagen designs the duplexes using the HiPerformance design algorithm it licensed from Novartis late last year (see RNAi News, 12/19/2003).

Details about the 2-for-Silencing duplexes can be found at http://www1.qiagen.com/Products/GeneSilencing/TwoForSilencing.aspx.


Ambion recently launched its mirVana kits for the preparation and purification of high specific activity radiolabeled RNA probes and small RNA markers.

According to the company, the purification kit allows for the clean up of 5’ end labeled RNA probes and is compatible with other in vitro transcription RNA probe synthesis kits. Radiolabeled probes prepared with the mirVana kit can be used for the detection of small RNAs fractionated by PAGE and miRNA detection by Northern blot, or by using the mirVana miRNA detection kit, said Ambion.

Details about the mirVana kits can be found at http://www.ambion.com/catalog/CatNum.php?1554.


Nature Reviews Genetics has introduced a new animation on RNAi on its website.

The animation, said Nature, was made in collaboration with Arkitek Studios, and includes a glossary feature that defines such terms as siRNA, RISC, and RdRp.

The animation can be viewed by going to http://www.nature.com/focus/rnai/animations/animation/animation.htm.

The Scan

NFTs for Genome Sharing

Nature News writes that non-fungible tokens could be a way for people to profit from sharing genomic data.

Wastewater Warning System

Time magazine writes that cities and college campuses are monitoring sewage for SARS-CoV-2, an approach officials hope lasts beyond COVID-19.

Networks to Boost Surveillance

Scientific American writes that new organizations and networks aim to improve the ability of developing countries to conduct SARS-CoV-2 genomic surveillance.

Genome Biology Papers on Gastric Cancer Epimutations, BUTTERFLY, GUNC Tool

In Genome Biology this week: recurrent epigenetic mutations in gastric cancer, correction tool for unique molecular identifier-based assays, and more.