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Dharmacon, Institut Pasteur, Molecula Research Laboratories, GenomeWeb

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Dharmacon said this week that it has launched the Protein Kinase siRNA Library, a library of ready-to-use Smartpool siRNA reagents and individual siRNA duplexes designed to knock down more than 550 genes involved in protein kinase production.

The company said that the library launch is part of a broader expansion of its siGENE list, which includes a presynthesized Smartpool siRNA reagent and four individual siRNA duplexes designed to silence over 1,500 genes.


Institut Pasteur recently introduced SIRNA, an online program to find siRNA duplexes in mRNA.

The program can be found at http://bioweb.pasteur.fr/seqanal/interfaces/sirna.html.


Molecula Research Laboratories recently introduced its iFect siRNA transfection reagent.

According to the company, iFect has been used to transfect siRNA into HEK293, HuH-7, B16 melanoma, CHO-K1, COS-1, COS-7, NIH3T3, SF-9, S2, primary human keratinocytes, primary rat aortic smooth muscle (WKY3M), and other cell lines.

Molecula has also begun offering free siRNA design and purification services with the purchase of RNA duplexes.


GenomeWeb, the publisher of RNAi News, has released the RNA Interference Technology Usage Report.

The 25-page report includes the results from a survey of 2,500 US-based subscribers to the GenomeWeb Daily News Service and Genome Technology magazine in academic, government, pharmaceutical, and biotechnology fields. The survey asked questions about usage of RNAi, the vendors from whom RNAi products are purchased, and the type of research done with the technology, among other things.

The Scan

Booster for At-Risk

The New York Times reports that the US Food and Drug Administration has authorized a third dose of the Pfizer-BioNTech SARS-CoV-2 vaccine for people over 65 or at increased risk.

Preprints OK to Mention Again

Nature News reports the Australian Research Council has changed its new policy and now allows preprints to be cited in grant applications.

Hundreds of Millions More to Share

The US plans to purchase and donate 500 million additional SARS-CoV-2 vaccine doses, according to the Washington Post.

Nature Papers Examine Molecular Program Differences Influencing Neural Cells, Population History of Polynesia

In Nature this week: changes in molecular program during embryonic development leads to different neural cell types, and more.