By Doug Macron

While recently announced plans
by three key big pharmas to alter their therapeutic RNAi efforts raised red flags for many industry watchers, many alliances for the gene-silencing technology remain ongoing.

Among these is a deal between Dicerna Pharmaceuticals and Japan's Kyowa Hakko Kirin, announced this week, that expands their drug-development partnership to include work in immunologic and inflammatory diseases.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.